The Colorado Rockies are struggling mightily in the 2025 MLB season, currently boasting a .160 winning percentage with an 8-42 record through 50 games. This dismal performance has led to a surge in betting against them, similar to the previous year's Chicago White Sox, who set a record with 121 losses. The Rockies have drawn the least moneyline bets of all MLB teams, making them a prime target for bettors looking to profit from their failures.

As they face formidable opponents like the New York Yankees and Chicago Cubs in upcoming series, bookmakers have adjusted their odds significantly, often placing the Rockies' opponents at -300 or higher on the moneyline. Bettors are creatively targeting the Rockies, betting on opposing team totals due to their lackluster offense. Despite a rare win against the San Diego Padres after a 21-0 defeat, the Rockies remain unlikely to recover this season.